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Biological Therapy is also referred to as Biotherapy or Immunotherapy. It is a kind of cancer treatment in which substances produced by the body or derived from living things are used to increase the immune system's capacity. It is also used to identify and eliminate cancer cells.
Immune Checkpoint Inhibitors, Cytokines, Cancer Vaccines, Adoptive Cell Transfer Therapy, and Monoclonal Antibodies are some of the examples of Biological Therapy treatment. Biological therapy in Bhubaneswar either targets certain molecules or processes implicated in the formation and progression of cancer or directly stimulates the immune system.
This treatment has demonstrated considerable potential in managing many forms of cancer and is frequently employed in conjunction with additional cancer therapies including Chemotherapy, Radiation Therapy, or Surgery and also ensuring patients follow a cancer-friendly diet.
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Immunotherapy is a cancer treatment that locates and eliminates cancer cells by stimulating the body's immune system. Your immune system recognises foreign objects and eliminates them, including malignant cells. Immunotherapy uses this mechanism and increases the ability of your immune system to identify and eliminate cancerous cells.
Immunotherapy is one of the highly effective cancer treatments that may extend a patient's life. Advancement is going on in this field with new immunotherapy medications being developed by medical experts to treat various types of cancer.
Your immune system works to protect your body from foreign invaders like viruses, allergies, and potentially cancerous cells on a daily basis. It possesses unique cells that continuously scan your body for invaders. They eradicate any damaged or cancerous cells they come into contact with. This prevents malignant tumours from proliferating and dispersing. However, cancer is a dynamic disease that keeps evolving to evade your body’s defence system. Malignant cells persistently seek ways to dodge the protective mechanisms of the immune system.
Whereas, Immunotherapy functions by:
Educating your immune system to detect and eliminate cancerous cells more effectively.
Assisting your body's production of immune cells that are capable of finding and eliminating cancer cells aids in fighting cancer.
Immunotherapy is frequently seen as the first-line or main therapeutic choice for treating various types of metastatic cancer by medical professionals. To enhance the efficacy of this therapy, it is commonly used in conjunction with Targeted therapy, Chemotherapy, or other cancer treatments. Different forms of Immunotherapy target distinct components of the immune system in the battle against cancer. These include Adoptive Cell Transfer Therapy, Checkpoint Inhibitors, Monoclonal Antibodies, and Cytokines. This method reflects the changing face of cancer treatment, where Immunotherapy is essential to improving the prognosis for patients with metastatic or advanced cancer.
Immunotherapy types include:
Checkpoint Inhibitors
Adoptive Cell Therapy (T-cell Transfer Therapy)
Monoclonal Antibodies
Cancer Vaccines
Immune System Modulators
Medical professionals commonly use Checkpoint Inhibitors to treat a wide variety of cancers. They are typically used to treat advanced cancer, cancer that has spread, cancer that is not surgically treatable, or cancer that does not respond to prior therapies. Checkpoint inhibitors are medications that can be taken in addition to chemotherapy or targeted therapy. The list of cancer types that can be treated with immunotherapy is expected to grow as more and more are identified:
Bladder cancer
Oesophageal cancer
Head and neck cancer
Cervical cancer
Hepatocellular carcinoma
High-risk triple-negative breast cancer
Melanoma
Mesothelioma
Non-small cell lung cancer
Kidney cancer
Immunotherapy causes adverse effects that can interfere with daily life, just like most cancer treatments do. Your immune system defends your entire body. Immunotherapy alters your immune system to make the process of combating cancer more successful.
However, immune cells have the potential to assault healthy cells, inflaming the surrounding tissue. This is an adverse event connected to immunity, or irAE. Severe irAEs occur in about 20% of Immunotherapy recipients. Along with this, the other common side effects are:
Fatigue
Itchy rash
Diarrhoea
Nausea and vomiting
Decreased thyroid hormone levels
Intravenous (IV) infusion is the usual method used to provide immunotherapy to patients, and its treatment frequency varies based on the regimen, from daily to monthly. Rest intervals are used in Cyclic Immunotherapy to enable the body to produce new and healthy cells in between treatments. The nature and stage of the cancer, the particular Immunotherapy medication used, and each patient's reaction to treatment all affect how long a course of treatment will last. Improved outcomes in cancer care are a result of this personalised strategy, which guarantees appropriate management based on each patient's needs and reaction to treatment.
Immunotherapy can potentially prolong life by slowing the spread of cancer. Not every patient responds well to treatment, even though, in some circumstances, it can reduce or stop the growth of malignancies. Patients respond differently to Immunotherapy, which emphasises the need for continued research and individualised treatment plans to maximise cancer patients' prognosis.
Immunotherapy is not always successful in treating all cancer types, and each patient's experience is different. Furthermore, the majority of Immunotherapy regimens have adverse consequences. If a medical professional recommends Immunotherapy, they will review its possible adverse effects and provide helpful coping mechanisms to manage them effectively. This individualised strategy optimises the balance between therapeutic advantages and potential side effects by ensuring patients are well-informed and supported throughout their treatment journey.
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