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Cushing Syndrome Treatment in Bhubaneswar

Cushing Syndrome

Cushing Syndrome Treatment in Bhubaneswar

Cushing syndrome is a condition caused by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. Cushing syndrome can lead to a range of symptoms, including weight gain, high blood pressure, diabetes, and changes in skin texture, among others.

Cushing syndrome treatment in Bhubaneswar involves a comprehensive approach to managing and addressing the underlying cause of cortisol excess. Treatment options may include medication to control cortisol production, radiation therapy, or surgical intervention to remove the tumour or adrenal glands responsible for the hormone overproduction. Our team of endocrinologists works closely with patients to determine the most effective treatment plan based on the severity of the condition and individual health needs.

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FAQ's

Aetiological factors contributing to the condition are listed below: 

  • Prolonged use of corticosteroid drugs is commonly prescribed for conditions such as rheumatoid arthritis and asthma.

  • Pituitary gland tumours, specifically adenomas, which are benign, can lead to increased production of the adrenocorticotropic hormone (ACTH).

  • Ectopic ACTH syndrome occurs when non-pituitary tumours, such as lung cancer, produce ACTH.

  • Benign or malignant tumours of the adrenal glands produce more cortisol.

  • Primary adrenal hyperplasia is a condition in which the adrenal glands become enlarged and produce excessive amounts of the hormone cortisol.

  • People are born with special traits that affect how their bodies control a hormone called cortisol. These traits are rare and are passed down from parents.

  • Gaining weight easily

  • Slender legs and arms

  • A rounded face

  • An increase of fat near the neck's base

  • Fat accumulation between the shoulders

  • Easy bruises

  • Broad purple stretch marks, mostly beneath the arms, on the hips, breasts, and abdomen

  • Weakened organs and tissues

If Cushing syndrome is left untreated, it may be lethal. In the absence of treatment, hypercortisolism can result in the following health issues:

  • Infections

  • Blood clots, particularly in the legs and lungs

  • Depression

  • Heart attack

  • Gaining weight

  • Difficulties concentrating or memory issues

  • Elevated blood pressure or cholesterol levels

  • Shattered bones

  • Impaired fasting glucose, prediabetes, or type 2 diabetes

To reduce symptoms and avoid difficulties, those with Cushing's syndrome must maintain a balanced diet. To preserve bone health, include foods high in calcium and vitamin D, such as cod liver oil, salmon, swordfish, tuna, fortified orange juice, fortified dairy and plant-based milk, sardines, beef liver, egg yolk, and fortified cereals. For calcium, these foods include dairy products, fortified orange juice, winter squash, edamame, tofu made with calcium sulphate, canned sardines, salmon with bones, almonds, and leafy greens. Limiting sodium and fatty meals is also crucial, and consulting a nutritionist can help make sure you're getting enough of the nutrients you need.

Treatment for high cortisol depends on the cause. If you're taking glucocorticoids, your doctor may lower the dose or switch medications. If a tumour is causing Cushing syndrome, surgery, radiation, or medication may be needed. You may work with several healthcare professionals to treat the tumour and its symptoms.

  • Adjusting for glucocorticoids: Reduce dosage or take a different kind of drug.

  • Surgery: Removal of ectopic, pituitary, or adrenal tumours; may necessitate short-term cortisol therapy.

  • Radiation: For incurable tumours with years-long side effects

  • Medication: Cortisol-lowering medications, such as ketoconazole

  • Chemotherapy: For metastatic malignant tumours

  • Follow-up care: Since healing might take two to eighteen months, ongoing observation with medical professionals is necessary.

Exercise helps people with Cushing's syndrome feel better physically, improve their mood, help control their weight, build stronger bones, and improve their general health. In addition to addressing some of the condition's psychological and physical side effects, it helps prevent weight gain and increase insulin sensitivity. Before beginning a fitness program, it's crucial to speak with a healthcare professional to be sure it's safe and suitable for your needs.

Yes, mental health issues can arise from Cushing's syndrome. A high cortisol level can frequently cause depression, anxiety, mood changes, and cognitive impairments. The impact of these symptoms on day-to-day functioning and general health can be profound. Treatment with medicine that lowers cortisol levels can help ease these mental health problems.

In Cushing's syndrome, bone disorders cause significant health problems. Around 30–50% of patients experience fractures, mainly in the spine, due to osteoporosis. Children with the condition may have stunted growth and reduced bone mass.

Osteoblast dysfunction contributes to bone loss, with decreased levels of serum markers like osteocalcin and alkaline phosphatase. Monitoring bone mineral density (BMD) is crucial, and DEXA scans are recommended.

Even after treatment, patients remain at higher risk of spine damage, requiring ongoing radiological monitoring. Glucocorticoid-induced osteoporosis recovery can be slow, with potential aid from alendronate to improve BMD. 

Cushing's syndrome is most commonly caused by prolonged, high-dose corticosteroid use. If you are taking corticosteroid medication, your doctor should closely monitor your cortisol levels. Cushing's syndrome cannot be prevented if it is caused by a tumour. However, after diagnosis, following a nutritious diet can help minimise symptoms.

 

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