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Chorionic Villus Sampling (CVS), also known as Chorionic Villus Biopsy, is a prenatal procedure that involves removing a sample of placental tissue to examine it for chromosomal abnormalities and other genetic issues. The placenta is a structure inside the uterus that provides the foetus with blood and nourishment from the mother.
The chorionic villi, which resemble small finger-like projections made of placental tissue, comprise the same genetic material as the developing foetus. Testing for additional genetic abnormalities and diseases may be done, depending on the family history and the availability of lab testing at the time of the procedure.
Typically, chronic villus sampling in Bhubaneswar is performed between 10 and 12 weeks of pregnancy. In contrast to another kind of prenatal test called amniocentesis, CVS doesn't give information on neural tube disorders such as spina bifida. Because of this, women who undergo CVS additionally require blood tests to screen for neural tube abnormalities at 16–18 weeks of pregnancy.
During the first trimester of pregnancy, Chorionic Villus Sampling may be used for chromosome and genetic testing. The following are some reasons a woman may choose to get Chorionic Villus Sampling :
Maternity age is above 35 years by the time the pregnancy is due
Possibility of sex-linked disorders
Prior ultrasonography with suspicious or unusual results
Unusual DNA test results without cells
Chorionic Villus Sampling can be done using two types of procedures, which are:
Transcervical: In this type of tissue sampling, tissues are extracted using a catheter placed into the cervix.
Transabdominal: In this procedure, tissues are obtained by inserting the needle through the abdomen and uterus.
Chorionic Villus Sampling can detect certain genetic conditions, such as chromosomal abnormalities. Foetal DNA is stored in these cell structures. Chorionic Villus Sampling can identify absent or extra chromosomes that have undergone major structural alterations. Chromosomal abnormalities of this type can result in birth defects and other issues. Chorionic Villus Sampling testing detects conditions such as:
Cystic fibrosis
Sickle cell disease
Tay-Sachs disease
Edward syndrome, or Trisomy 18
There are multiple benefits associated with CVS testing, including:
Accurate results: You can rely on the results of the test to make important healthcare decisions.
Critical information: If you and your partner are at higher risk of having a baby with a genetic disorder or other problem, you may want to know as soon as possible what's going on with the foetus. Having this information can help you make the right decision, such as planning for any special treatment your baby might require after birth or deciding not to proceed with the pregnancy.
Earlier knowledge: By doing CVS earlier in the pregnancy than amniocentesis, you can make decisions at the beginning of the pregnancy.
You receive genetic counselling before the test from a maternal-foetal medicine specialist or a licenced genetic counsellor. You and a genetic counsellor talk about the advantages and disadvantages of the operation. To determine your gestational age or how many weeks pregnant you are, you may need to take an ultrasound. When you're between 10 and 13 weeks pregnant, this is the ideal gestational age to undergo CVS testing.
Chorionic Villus Sampling (CVS) is usually carried out in the following way:
Guidance: A needle or catheter is placed into the cervix or abdomen using ultrasound technology.
Sample Collection: The tissue that will give rise to the placenta, the chorionic villi, is sampled in tiny pieces.
Analysis: Next, the material is examined to check for any diseases or genetic anomalies.
Monitoring: Following the surgery, the woman is monitored for any complications.
For some women, CVS causes no pain. Some experienced cramps during the sample collection that resembled menstrual cramps. Some women describe the experience of undergoing tests through their cervix as similar to a Pap smear.
After CVS, you can rest for ample time. Following the test, you may experience cramps or bleeding for a few hours. You may consider avoiding physical activity and sexual activity for the day. Additional risks consist of:
Rh sensitisation: It is a disorder that occurs when your blood mixes with the newborn blood. To prevent your immune system from rejecting the blood of your infant, you could require an injection.
Infection: Although it is uncommon, CVS can also lead to an infection.
Find medical assistance following CVS testing if cramps, pain, or bleeding continue to persist or worsen. Additionally, you need to contact your healthcare provider if you have:
Chills
Fever
Contractions
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