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Plasma Exchange Therapy

Plasma Exchange Therapy Bhubaneshwar

Plasma Exchange Therapy, also called Plasmapheresis, is a procedure used by medical professionals to extract plasma from a patient’s blood and replace it with healthy plasma or other fluids. The plasma consists of blood, electrolytes, salt, and proteins.

The therapy involves extracting blood and separating the plasma from the blood using a machine. Subsequently, a fluid is added to replace the plasma and administered back to the patient. Therapeutic Plasma Exchange (TPE) is beneficial for treating various conditions such as hyperviscosity syndrome, thrombotic thrombocytopenic purpura, haemolytic uremic syndrome, idiopathic thrombocytopenia, renal and rheumatologic diseases, as well as neurological conditions such as GBS (Guillain-Barre’ Syndrome) and chronic inflammatory demyelinating polyneuropathy.

Plasma Exchange Therapy is a safe and reliable procedure to treat various neurological and blood conditions. However, there is a potential for developing several complications, such as hypocalcaemia, hypothermia, and hypertension. Our medical experts at Manipal Hospitals, Bhubaneswar, Odisha, ensure comprehensive and effective care for all patients wanting to undergo the procedure.

FAQ's

If any substances in your blood are affecting your health and well-being, Plasma Exchange Therapy will help remove these substances. The therapy is recommended as a part of your treatment plan.

This procedure is used by medical professionals to treat blood malignancies, neurological conditions, and a range of blood problems. They may combine plasma exchange with other treatments, or they could use it as a first-line or initial treatment. Plasma exchange is another tool that providers might utilise to aid in organ transplant recovery.

In order to eliminate dangerous antibodies from patients' plasma, providers may employ plasma exchange. Among the illnesses treated are:

  • Multiple Sclerosis (MS) patients experience severe symptoms brought on by plasma proteins attacking their bodies. This is managed with Plasma Exchange Therapy. 

  • Myasthenia Gravis: This condition arises when healthy tissue is attacked by antibodies meant to fight foreign invaders. The aberrant antibodies are filtered out via plasma exchange.

  • Guillain-Barré Syndrome: An immune system attacking nerves results in this illness. The antibodies in your plasma that are targeting your immune system are filtered away by plasma exchange.

Providers treat the following blood diseases using Plasma Exchange Therapy:

  • Cryoglobulinemia: This disorder is brought on by the clumping of proteins in the blood called cryoglobulins, which clog arteries, cause inflammation, and damage organs. In order to get rid of cryoglobulins that could otherwise clog your arteries, providers use Plasma Exchange Therapy.

  • Thrombocytopenic Purpura: Blood clots in tiny arteries all over the body are a symptom of thrombotic thrombocytopenic purpura. Your blood may be cleansed of harmful plasma by the providers via plasma exchange. Without taking any of your blood, they might use donor plasma.

Your healthcare practitioner might suggest you do the following if you are receiving plasma exchange: Start consuming noncarbonated drinks 72 hours before your therapy. A good idea is to eat something approximately one hour prior to your therapy. When receiving treatment, dress comfortably and bring a book or music to pass the time. After your treatment, make arrangements for someone to drive you home.

A catheter with two ports will be inserted into a large vein in your chest or groin. During therapy, blood will be removed from one port of the catheter and will be passed through the plasma therapy machine, and the blood will be later returned through another port.

The TPE machine is responsible for separating plasma from blood cells. The separated plasma is then discarded, and the blood is returned through the catheter with plasma replacement fluid.

An exchange of plasma could take several hours.

No, it's not unpleasant; however, when medical professionals insert intravenous lines in your arms, you might feel some discomfort, tingling, or numbness sensation.

  • Transplant Rejection: You will receive Plasma Therapy every day for a period of 3 to 5 days. However, the total number of required sessions depends on the severity of transplant rejection.

  • For Neurological Diseases: Depending on the severity of symptoms, your therapy sessions may be administered every other day, once a week, twice a month, or every month.

  • For Kidney and Blood Disease: Depending on the diagnostic tests, the number of sessions you require will be determined by the healthcare provider.

Even though complications with Plasma Therapy are rare, potential complications that may develop due to the therapy are:

  • A drop in blood pressure from having the fluid removed may cause dizziness, blurred vision, cold sweats, and abdominal cramps.

  • An imbalance in fluid electrolytes may result in tingling sensations around your mouth or fingers or may cause you to even develop muscle cramps.

  • Reaction to replacement fluid.

  • Due to the removal of clotting factors with plasma, there can be an increased risk of bleeding.

  • You may be at increased risk for developing infection from catheter insertion or from taking immunosuppressants.

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