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Cushing's syndrome is a condition that happens when your body produces an excessive amount of the cortisol hormone over time. Cortisol is also known as the "stress hormone" because it helps your body adapt to stress. Cortisol also helps to maintain blood pressure, control blood glucose (also known as blood sugar), reduce inflammation and transform food into energy. Cortisol is produced by the adrenal glands, which are two tiny glands located above the kidneys. Cushing's syndrome is most common in adults between the ages of 20 and 50, but it can also affect children. Cushing's syndrome may be present in people with type 2 diabetes and persistently high blood glucose levels, as well as high blood pressure.
Cushing's syndrome affects almost three times more women than men. People who use medications called glucocorticoids, which are related to cortisol, can develop Cushing's syndrome. Manipal Hospitals provides specialised care and comprehensive cushing syndrome treatment in Kolkata with options for managing Cushing's syndrome, ensuring personalised care and support for patients facing this condition.
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Cushing's syndrome (CS) is a rare condition in which the adrenal gland(s) produce an excessive amount of a hormone called cortisol. The most common cause of CS is a tumour or mass in the pituitary gland; however, tumours in the adrenal glands can also cause it. People with Cushing's syndrome may notice their faces becoming round ("moon face"), gaining weight in odd ways, bruising easily, or feeling weak, fatigued, and depressed. Both men and women may experience fertility issues. CS is most commonly encountered in people between the ages of 20 and 50.
Cushing's syndrome frequently occurs when the pituitary gland produces an excessive amount of adrenocorticotropic hormone (ACTH). This causes the adrenal glands to produce excessive corticosteroids. Cushing's syndrome is fairly uncommon.
Cushing's syndrome can result in health issues such as:
Cushing's syndrome is normally curable, although it can be fatal if left untreated.
The signs and symptoms of Cushing's syndrome differ.
Cushing's disease continues to be an issue, even after treatment. Even those who are cured endure a lengthy road before life returns to normal. After surgery to remove a Cushing's tumour, the body's cortisol levels drop dramatically, and it takes many months for the body to resume normal production levels.
Cortisol is always needed in the body. It controls your respiration, converts your food into energy, regulates your blood sugar, and helps you deal with stress, among other things. Cortisol is not your body's adversary, yet, too much of it might be. However, you cannot survive without cortisol. If you are using glucocorticoids or steroids, your healthcare professional should closely check your cortisol levels. Unfortunately, there is no method to avoid a tumour that causes Cushing syndrome (hypercortisolism).
Living with Cushing's syndrome can present challenges, but effective treatment options and supportive healthcare providers can help maintain your quality of life. Treatment aims to cure the syndrome and reduce symptoms caused by excess cortisol. Emotional and social difficulties may arise due to physical changes like baldness, excessive hair growth, and weight gain in specific areas like the face and neck ("moon face" and "buffalo hump"), which can affect self-esteem and social interactions. However, over time, treatment can improve these symptoms. Cushing's syndrome may also lead to mental health issues such as depression. Seeking counselling and medication from a psychiatrist can be beneficial in managing the emotional impact of hypercortisolism.
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