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CPsy. Ruchi Sharma

Consultant - Clinical Psychologist

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CPsy. Ruchi Sharma

Consultant - Clinical Psychologist

Manipal Hospitals, Delhi

The Science Behind Anxiety : What Happens In Your Brain & How to Manage it

Posted On: Feb 11, 2025
blogs read 6 Min Read
Science Behind Anxiety

Anxiety is a natural response to stress, but for many, it can become overwhelming and disruptive. Understanding what happens in your brain during anxiety disorders can empower you to manage it more effectively. In this article, we will explore the neuroscience of anxiety, its aetiology, prevalence, and risk factors, and provide practical ways to reduce its impact on your daily life.

Science Behind Anxiety

 

The Neuroscience of Anxiety

Anxiety originates in the brain and is driven by a complex interaction between different regions and chemicals. Here’s a closer look at the key players:

1. The Brain’s Alarm System: The Role of the Amygdala

The amygdala is a small, almond-shaped cluster of neurones deep in the brain. It plays a crucial role in detecting threats and triggering the body’s fight-or-flight response. When you encounter a stressful situation, the amygdala signals your body to release stress hormones like cortisol and adrenaline. This response is designed to keep you alert and ready to react.

However, in individuals with chronic anxiety, the amygdala may be overactive, perceiving threats where none exist. This can lead to generalised anxiety disorder (GAD) and chronic feelings of worry and fear.

2. The Prefrontal Cortex: Your Brain’s Rational Thinker

The prefrontal cortex is responsible for rational thinking and decision-making. It helps regulate the amygdala’s response and allows you to assess whether a threat is real or imagined. In people with anxiety disorders, the connection between the prefrontal cortex and the amygdala may be weaker, making it harder to calm down after a perceived threat.

3. The Role of Neurotransmitters: Chemical Messengers of Anxiety

Neurotransmitters are brain chemicals that influence mood and emotions. Three key neurotransmitters play a role in anxiety:

  • Serotonin: Low levels of serotonin are linked to increased anxiety and depression.

  • Dopamine: This neurotransmitter affects motivation and pleasure. An imbalance can contribute to anxiety disorders.

  • GABA (Gamma-Aminobutyric Acid): GABA is an inhibitory neurotransmitter that helps calm neural activity. A deficiency in GABA can lead to heightened anxiety and stress.

Etiology of Anxiety & Risk Factors

Anxiety disorders develop due to a combination of genetic, environmental, and psychological factors. Some key contributors include:

Risk Factor

Description

Genetics

A family history of anxiety disorders can increase the likelihood of experiencing it.

Brain Chemistry

Imbalances in neurotransmitters play a crucial role.

Personality Traits

Highly sensitive, perfectionistic, or introverted individuals may be more prone to anxiety.

Trauma & Stress

Childhood trauma, major life changes, or chronic stress can trigger anxiety disorders.

Medical Conditions

Chronic illnesses, hormonal imbalances, and neurological disorders can contribute to anxiety.

Substance Use

Alcohol, caffeine, and recreational drugs can worsen anxiety symptoms.

Prevalence of Anxiety: A Rising Lifestyle Disorder

Anxiety disorders are among the most common mental health conditions worldwide. Studies indicate that anxiety affects millions of people, with increasing prevalence among younger populations. The rise of social media stress, academic pressures, work stress, and economic uncertainties have contributed to making anxiety a lifestyle disorder.

Demographic

Anxiety Prevalence

Global

1 in 13 people suffer from anxiety (WHO).

Young Adults & Teens

Higher rates due to social comparison, performance pressures, and digital overstimulation.

Women

Nearly twice as likely to experience anxiety as men due to hormonal fluctuations and societal expectations.

The Spectrum of Anxiety: Different Types

Anxiety manifests in various forms, and recognising different types can help in seeking the right treatment.

  1. Generalised Anxiety Disorder (GAD): Chronic and excessive worry about everyday activities.

  2. Social Anxiety Disorder: Intense fear of social interactions and being judged by others.

  3. Panic Disorder: Sudden episodes of intense fear accompanied by physical symptoms like rapid heartbeat and shortness of breath.

  4. Phobias: Irrational fears of specific objects, places, or situations.

  5. Obsessive-Compulsive Disorder (OCD): Repetitive thoughts and compulsive behaviors to reduce anxiety.

  6. Post-Traumatic Stress Disorder (PTSD): Anxiety triggered by past traumatic experiences.

How to Manage Anxiety Effectively

Science Behind Anxiety

1. Deep Breathing Techniques

Practicing deep breathing can help calm the nervous system. A simple technique is the 4-7-8 breathing method:

  • Inhale through your nose for 4 seconds.

  • Hold your breath for 7 seconds.

  • Exhale slowly through your mouth for 8 seconds.

  • Repeat several times to promote relaxation.

2. Exercise as a Natural Anxiety Reliever

Physical activity releases endorphins, which are natural mood boosters. Activities like jogging, yoga, or even a short walk can significantly reduce anxiety levels.

3. The Power of Journaling

Writing down your thoughts helps process emotions and reduce anxious feelings. Try journaling about what’s causing your anxiety and possible solutions.

4. Mindfulness & Meditation

Mindfulness meditation helps train your brain to stay present and reduces excessive worry. Apps like Headspace or Calm offer guided meditations for anxiety relief.

5. The Role of Nutrition in Anxiety

Your diet can impact your anxiety levels. Some tips for an anxiety-friendly diet include:

  • Eating more omega-3 fatty acids (found in fish, flaxseeds, and walnuts)

  • Reducing caffeine and sugar intake

  • Including probiotic-rich foods like yogurt and kimchi for gut health

6. Cognitive Behavioral Therapy (CBT)

CBT is a highly effective therapy that helps reframe negative thought patterns. It teaches practical coping skills to manage anxiety triggers.

7. The Importance of Sleep

Lack of sleep can make anxiety worse. To improve sleep:

  • Stick to a regular sleep schedule.

  • Avoid screens before bedtime.

  • Try relaxation techniques like reading or taking a warm bath.

While self-help strategies can be effective, professional intervention is sometimes necessary. If anxiety symptoms interfere with your daily life, seeking medical assistance from experts can make a significant difference.

Conclusion

At Manipal Hospital Dwarka, we offer comprehensive mental health services with experienced specialists in psychiatry and psychology to help manage anxiety disorders. Our team of experts provides personalised treatment plans, including therapy, medication, and holistic wellness programs.

Contact us for expert guidance. Take the first step towards a healthier mind. Book an appointment with our expert at Manipal Hospital Dwarka today. 

FAQ's

Symptoms include excessive worry, restlessness, fatigue, rapid heartbeat, and difficulty concentrating.
 

While it may not be completely eliminated, it can be effectively managed with the right strategies.

Exercise, deep breathing, meditation, proper nutrition, and adequate sleep are beneficial.
 

Yes, caffeine can increase heart rate and trigger anxiety symptoms in some individuals.

Yes, genetics can play a role, but environmental factors also contribute significantly.

If anxiety interferes with daily life, relationships, or work, seeking professional help is recommended.

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