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Manipal Hospitals, Dhakuria, offers advanced Cytoreductive Surgery within its Gynaecologic Oncology department, specialising in the treatment of complex gynecologic cancers, including ovarian, uterine, and cervical cancers.
Cytoreductive Surgery (CRS), also known as Debulking Surgery, is a procedure aimed at reducing the volume of cancerous tissue in the body. The primary goal is to remove as much of the tumour mass as possible. This type of surgery is often used in the treatment of advanced or metastatic cancers, where the cancer has spread within the abdominal cavity, such as ovarian cancer, colorectal cancer, and peritoneal carcinomatosis.
At Manipal Hospitals, a multidisciplinary team of experienced oncologists, surgeons, and support staff ensure comprehensive preoperative assessment, meticulous surgical intervention, and attentive postoperative care. We use state-of-the-art technology and personalised treatment plans to ensure the best possible outcomes for our patients. If you or a loved one is considering Cytoreductive Surgery for Ovarian Cancer in Dhakuria, we are here to support you every step of the way.
Cytoreductive Surgery (CRS) is a surgical procedure aimed at reducing the number of cancer cells in the body by removing as much of the tumour mass as possible. Any remaining cancer after surgery is treated with additional therapies, such as Chemotherapy, Radiation Therapy, or Targeted Therapy. This approach leads to better outcomes and an improved quality of life for the patient.
You might be a candidate for Cytoreductive Surgery if you have:
Advanced-stage cancers like ovarian, colorectal, or peritoneal carcinomatosis.
Spread of cancer inside the abdominal cavity.
Good overall health to tolerate a major surgical procedure.
Tumours are considered resectable, meaning they can be surgically removed to a significant extent.
Cytoreductive Surgery is a major surgical procedure, and it is normal to be concerned about pain. During the surgery, you will be given anaesthesia, and you won't feel any pain. After the surgery, when anaesthesia wears off, you may feel some discomfort. Pain relief medications, including opioids, non-opioid analgesics, and anti-inflammatory drugs, will be administered as needed.
The diagnostics tests performed before Cytoreductive Surgery are as follows:
Imaging Studies
CT scans: Provide detailed images of the abdominal cavity and help identify the size, location, and spread of tumours.
MRI: Offers high-resolution images of soft tissues to see if cancer has spread to organs and the lining of the abdominal cavity (peritoneum).
PET Scan: Detects metabolic activity of cancer cells and helps in identifying active disease areas that might not be visible on CT or MRI.
Ultrasound: Used to evaluate specific areas, such as the liver or pelvis, for tumour involvement.
Laboratory Tests
Blood Tests: Includes complete blood count (CBC), liver function tests, kidney function tests, and tumour markers (e.g., CA-125 for ovarian cancer) to evaluate the patient's general health and detect any abnormalities.
Biopsies
Tissue Biopsy: A sample of tissue may be taken from the tumour to confirm the type of cancer and its characteristics.
Laparoscopy: A minimally invasive procedure where a camera is inserted into the abdomen to visually inspect and sometimes biopsy tumours.
During the Cytoreductive Surgery, you can expect:
You will be given general anaesthesia to ensure you are unconscious and pain-free throughout the procedure.
You will be positioned on the operating table in a way that allows the surgeon optimal access to your abdominal area.
The surgeon will make a large incision in your abdomen to open the abdominal cavity and thoroughly examine the abdominal organs and tissues to determine the extent of the cancer spread.
The surgeon proceeds to remove as many visible tumours as possible, which may involve resecting parts of or entire organs affected by cancer, such as portions of the intestines, spleen, liver, or stomach, and stripping affected areas of the peritoneum (the lining of the abdominal cavity). Precise techniques are employed to minimise damage to surrounding healthy tissues.
In some cases, after tumour removal, a heated Chemotherapy solution is introduced into the abdominal cavity in a process known as Hyperthermic Intraperitoneal Chemotherapy (HIPEC). This solution is circulated throughout the abdomen for about 60-90 minutes, with the heat enhancing the Chemotherapy's effectiveness in killing the remaining cancer cells. The solution is then drained from the abdomen.
After tumour removal and any optional HIPEC treatment, the abdominal cavity is thoroughly rinsed to remove any remaining debris or Chemotherapy solution. The incision is then carefully closed with sutures or staples, and sometimes drains are placed to remove any excess fluid that accumulates post-surgery.
The duration of Cytoreductive Surgery can vary depending on several factors, including the extent of the cancer, the complexity of the procedure, and whether Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is included. Generally, you can expect the surgery to last between 6 to 12 hours.
Recovery from Cytoreductive Surgery includes:
A one- to two-week hospital stay for close observation and initial recovery.
Postoperative care includes managing pain, taking care of surgical wounds, and progressively getting back to eating and exercising.
Regular follow-up appointments to monitor recovery and continue cancer treatment if needed.
The main benefits include:
By removing as much of the tumour mass as possible, Cytoreductive Surgery helps to decrease the number of cancer cells in the body, making subsequent treatments more effective.
Studies have shown that patients undergoing Cytoreductive Surgery, particularly when combined with HIPEC, can experience improved survival rates compared to those receiving traditional treatments.
By reducing tumour size and easing symptoms caused by large tumour masses, patients often experience a better quality of life post-surgery.
As with any major surgery, Cytoreductive Surgery carries potential risks and complications, including infection, bleeding, and impacts on organ function.
While it’s not always possible to completely prevent cancer, there are several steps you can take to reduce your risk of developing cancers that may require Cytoreductive Surgery, such as ovarian, colorectal, appendiceal, peritoneal mesothelioma, gastric, and primary peritoneal cancers.
Eat plenty of fruits and vegetables.
Reduce intake of processed meats and red meats to lower the risk of colorectal cancer.
Limiting alcohol consumption and quitting smoking can reduce the risk of several types of cancer.
Aim for at least 150 minutes of moderate aerobic activity or 75 minutes of vigorous activity each week.
If you have a family history of certain cancers, genetic testing and counselling can help assess your risk and guide preventive measures.
For more information or to schedule a consultation, please contact our Oncology Department at Manipal Hospitals, Dhakuria, or visit our website.
Contact no: 1800 102 5555
Visit: https://www.manipalhospitals.com/specialities/gynaec-oncology/
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