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A variety of cutting-edge methods are used in non-surgical cancer therapies to target and eradicate malignant tumours with the least amount of harm to the surrounding healthy tissues. These medical procedures, referred to as Radiation Therapy, use high-energy radiation to either kill or stop the development of cancer cells.
External Beam Radiation is a popular type of Radiation Therapy in which a concentrated radiation beam is sent from outside the body to target the tumour. With this method, the tumour may be precisely targeted without endangering the surrounding tissues or organs.
Another method is to insert radioactive sources into or close to the tumour via a procedure called Brachytherapy. This reduces exposure to healthy tissues by enabling the delivery of a stronger radiation dosage directly to the cancer spot.
Depending on the kind and stage of cancer, Radiation Therapy may be used either alone or in conjunction with other therapies, including Immunotherapy, Chemotherapy, or Surgery. It is frequently used to treat a variety of malignancies, including those of the brain, breast, lung, and prostate.
External Beam Radiation Therapy (EBRT), Brachytherapy, Radioembolization, Radiofrequency Ablation (RFA), Stereotactic Radiosurgery (SRS), and Stereotactic Body Radiation Therapy (SBRT) are the main non-surgical cancer therapies. Radiation may be delivered precisely to malignant tissues while causing the least amount of harm to nearby healthy organs. The kind, size, location, and patient-specific characteristics of the tumour all play a role in the customised selection of these therapies. Treatment results can be enhanced when these techniques are used in conjunction with other cancer treatments, such as Immunotherapy or Chemotherapy.
External Beam Radiation Therapy (EBRT) uses a linear accelerator to deliver radiation externally over a number of sessions. It is appropriate for tumours that are extensive or deeply seated. On the other hand, Brachytherapy, which is frequently used for superficial or localised tumours, delivers precision targeting and a shorter treatment time by inserting radioactive sources into or close to the tumour. The two techniques work well together; when combined, they offer extensive radiation treatment choices for different cancer kinds and sites.
Radiation Therapy is a useful non-surgical approach that effectively manages cancer while protecting healthy tissues and organs. The benefits of Radiation Therapy for the treatment of cancer include the preservation of organs, low invasiveness, adaptability, focused therapy, ease of access for outpatients, and pain alleviation. These advantages improve patient comfort and quality of life, reduce adverse effects, and improve treatment results.
For many cancers, including those of the prostate, breast, lung, head and neck, cervical, rectal, brain tumours, lymphomas, and bone metastases, Radiation Therapy is the first line of treatment. Depending on the stage of the cancer, it offers either curative or palliative advantages, with the least amount of side effects, good disease management, and possibly a cure. These many uses highlight the critical role that radiation treatment plays in managing cancer in a variety of tumour forms and patient situations.
Radiation Therapy uses meticulous treatment planning, which involves DNA damage induction and cell cycle sensitivity, to target cancer cells accurately while preserving healthy tissues. While radiosensitivity differences in cancer cells require personalised treatment options, fractionation helps healthy tissues recover in between treatments. Accuracy is ensured by techniques such as IGRT (Image-guided Radiation Therapy), which controls organ movements during therapy. Together, these systems maximise tumour management and reduce adverse effects, improving patient outcomes and quality of life.
To increase treatment efficacy and improve results, Radiation Therapy can be coupled with Immunotherapy, Hormone Therapy, Targeted Therapy, Chemotherapy, Surgery, and supportive treatments. By stimulating the immune system, inhibiting tumour development pathways, or making cancer cells more susceptible to radiation, these mixtures operate in concert to target cancer cells. Oncologists can address tumour heterogeneity and optimise therapeutic results while minimising toxicity and maintaining cancer patients' quality of life by combining several therapy modalities.
Radiation treatment is chosen for cancer patients after taking into account the patient's health, the kind and stage of the disease, and the location of the tumour. The goal of the treatment, prior treatments, and technical advancements all influence the decision-making process. It's important to consider the patient's preferences and tolerance for any negative effects. Oncologists customise therapies to maximise results while minimising toxicity, guided by clinical criteria. Tailored strategies guarantee efficient cancer treatment, incorporating Radiation Therapy into multimodal strategies where necessary.
Potential side effects of Radiation Therapy in cancer treatment include fatigue, skin changes, hair loss, nausea, digestive issues, urinary symptoms, sexual dysfunction, oedema, pain, and the risk of secondary cancers. Long-term effects like tissue fibrosis or cognitive changes may also occur. Close monitoring and supportive care can help manage these side effects, improving the overall treatment experience for cancer patients.
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