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Hyperthermic Intraperitoneal Chemotherapy in Dhakuria

Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Dhakuria, West Bengal

Patients with abdominal tumours are finding new hope with a surgical procedure called Hyperthermic (or heated) Intraperitoneal Chemotherapy, or HIPEC. Certain abdominal malignancies can be treated with a two-step procedure called Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Surgery. 

The surgeon will first remove any visible tumours. We refer to this process as Cytoreductive Surgery or CRS. After that, a hot liquid containing Chemotherapy medications will be poured into your belly to target any leftover cancer. The medications will be removed from your stomach after enough time has passed, your surgical wound will be sutured, and you will be transferred to critical care to continue healing. You won't experience any pain throughout the Hyperthermic Intraperitoneal Chemotherapy (HIPEC) treatment in Dhakuria, because you'll be under general anaesthesia. 

However, there are certain adverse consequences of Hyperthermic Intraperitoneal Chemotherapy. It is necessary to prepare patients to be fed via an IV or feeding tube for approximately two weeks while their digestive systems heal from the high dosage of Chemotherapy.
 

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FAQ's

HIPEC stands for Hyperthermic Intraperitoneal Chemotherapy, a specialised cancer treatment used primarily for cancers within the abdominal cavity, such as peritoneal carcinomatosis, ovarian cancer, or colorectal cancer with peritoneal spread.

In this procedure:

  • After surgical removal of visible tumours (cytoreductive surgery), a heated chemotherapy solution is introduced directly into the abdominal cavity.

  • The solution is heated to approximately 41-43°C (105.8-109.4°F) to enhance the effectiveness of the chemotherapy.

  • It is circulated for about 60-90 minutes to target any remaining microscopic cancer cells.

  • HIPEC minimises systemic side effects while delivering high doses of chemotherapy directly to the affected area, making it a promising option for certain advanced or recurrent cancers.

The surgical process is often called MOAS (Mother of All Surgeries) since it can be similar to having multiple major surgeries, depending on the amount of malignant tissue and impacted organs that need to be removed.
 

One of HIPEC's main benefits over traditional Chemotherapy is the fact that it has fewer adverse effects. HIPEC is less likely to harm healthy organs and tissues since it is given directly to the cancer spot rather than circulating throughout the bloodstream. Nevertheless, HIPEC can still result in a few adverse effects, such as: 
Painful emesis (throwing up) 

  • Diarrhoea 

  • Constipation 

  • Bloating 

  • Loss of weight 

  • Having trouble falling asleep 

The advantages of HIPEC are:

  • HIPEC delivers chemotherapy directly into the abdomen, targeting cancer cells more effectively while reducing side effects in the rest of the body.

  • The chemotherapy is heated, which helps it work better by improving absorption and making cancer cells more sensitive to treatment.

  • Unlike regular chemotherapy, HIPEC focuses on the abdomen and minimises side effects like hair loss or nausea.

  • It is combined with surgery to remove visible tumours and treat any remaining cancer cells, reducing the chances of cancer coming back.

  • HIPEC can help some patients with advanced abdominal cancers live longer and enjoy a better quality of life.

  • Since HIPEC is done during surgery, it provides a one-time, concentrated treatment instead of requiring multiple sessions.

  • Three primary components make up the procedure: HIPEC, Cytoreductive Surgery, and Exploration. 

  • The only period with a set limit is the HIPEC period (60-120 minutes). 

  • The other two components of the treatment vary depending on the extent of the disease affecting several abdominal organs and necessitating repeated resections, as well as the existence and extension of past adhesions. In general, the entire process takes four to ten hours.

The Chemotherapy fluid can more effectively kill microscopic cancer cells by penetrating the afflicted tissue when HIPEC is used. When compared to surgery or chemotherapy alone, HIPEC performed in conjunction with surgical tumour removal is linked to better results for some cancer types, particularly appendiceal malignancies. 
 

Catheters are used to directly inject HIPEC into the abdominal cavity. Chemotherapy aims to destroy cancer cells while leaving healthy cells intact. Because normal cells die at roughly 111.2°F and malignant cells die at approximately 104°F, HIPEC is delivered within a precise temperature range.
 

Your surgeon will remove any visible tumours from your stomach cavity during this treatment, and any cancer cells that remain will be targeted with a heated, highly concentrated chemotherapy solution. HIPEC recovery typically takes at least three months.
 

The effectiveness of HIPEC varies depending on factors such as the type and stage of cancer, the patient’s overall health, and how well the cancer responds to treatment. HIPEC is designed to target cancer cells directly and may significantly reduce the risk of recurrence in certain cancers. However, its long-term effectiveness differs for each individual and should be discussed with the treating oncologist.
 

Other surgical techniques, such as Targeted Therapy, Immunotherapy, Radiation Therapy, and Systemic Chemotherapy, may be options for HIPEC, depending on the situation. Decisions on a patient's course of treatment are determined by evaluating their unique circumstances and consulting medical experts. 
 

You can expect the following:

  • Medical Check-up: You’ll have tests and scans to make sure HIPEC is right for you.

  • Consultation: Meet with your doctor to discuss the procedure and ask any questions.

  • Stop Certain Medications: Your doctor may ask you to stop some medications before surgery.

  • Fasting: You’ll need to avoid eating or drinking for several hours before surgery.

  • Pre-surgery Care: You may receive antibiotics or other treatments to help you prepare.

  • Recovery Preparation: Arrange for help at home as you recover after surgery.

  • Mental Preparation: It’s helpful to talk with family or a counsellor to feel more at ease.

  • Pack for the Hospital: Bring essentials like clothes and personal items for your stay.

A person's decision to have HIPEC is influenced by several variables, such as their personal preferences, general health, and the kind and stage of their cancer. To find the best course of action for your unique circumstances, you and your medical team must have a thorough discussion.
 

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