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A Kidney Transplant is a surgical procedure where one kidney is removed and replaced with another. This procedure helps people whose kidneys are no longer working properly due to disease or injury. Kidney transplants can be from a living or deceased donor. A living donor donates one of their kidneys. In contrast, a deceased donor had passed away and donated their organs before they died. A kidney transplant can help many people with kidney conditions live longer, healthier lives. Chronic Kidney Disease is a severe condition that affects about 10% of the world's population. As per estimates, more than 7.8 million people in India suffer from Chronic Kidney Disease, with over 1.7 million deaths annually. Manipal Hospitals is the best kidney transplant hospital in Kharadi, Pune, with state-of-the-art diagnostic and treatment facilities to enable kidney transplants.
Manipal Hospitals is the best kidney transplant hospital in Pune, Kharadi. Our renal sciences department offers comprehensive medical care and treatment of the kidneys. We offer state-of-the-art diagnosis facilities for all kidney disorders, including Kidney Failure, Renal Failure, Kidney Stones, Dialysis Treatment, Kidney Transplant Surgery (Kidney Transplant), and Prostate Cancer Treatment.
Our team includes highly skilled Nephrologists & Urologists with experience in treating all kinds of kidney-related diseases. We prefer Non-invasive and minimally invasive procedures for patient safety and speedy recovery.
Who needs Kidney Transplant?
The kidneys are bean-shaped organs on the spine's either side, below the rib cage. The kidneys remove waste products by filtering the blood. They also help regulate electrolyte levels, produce hormones that help keep blood pressure within a normal range and control Red Blood Cell production.
Kidney problems can cause various symptoms, including swelling (oedema), frequent urination, fatigue and weakness, nausea and vomiting, pain in your sides or lower back (Flank Pain), muscle cramps or spasms due to dehydration from too much urinating.
Common conditions affecting the kidneys include Cystinuria (a genetic disorder), Diabetes Mellitus (diabetes), Hypertension (high blood pressure), Polycystic Kidney Disease (PKD), Glomerulonephritis (inflammation of the glomeruli) and Acute Tubular Necrosis (ATN).
The two most common types of kidney failure are:
End-Stage Renal Disease (ESRD) is a condition in which the kidneys have failed and cannot filter waste products from the blood. Kidney failure leads to an accumulation of toxins in the body that can cause serious complications.
ESRD typically results from Diabetes, Hypertension, Glomerulonephritis, Polycystic Kidney Disease, or long-term use of certain medications. People with ESRD must stay on Dialysis or a Kidney Transplant to stay alive.
Chronic Kidney Disease (CKD) is a progressive disease that affects the kidneys. The kidneys filter and remove waste products from the body.
The onset of CKD can be slow and gradual, with symptoms that often mimic those of other unrelated conditions, such as anaemia or fatigue. The symptoms become severe with disease progression. They include leg swelling, shortness of breath, nausea, vomiting and abdominal pain.
CKD may lead to kidney failure, which can cause a person to die if not treated. Get the finest consultation from our team of experts at the best kidney transplant hospital in Pune.
Diagnostic Procedures
Ultrasound visualises soft tissues and organs, including the kidneys using high-frequency sound waves.
Ultrasound assesses the health and function of the transplanted kidney, as well as checks for complications such as rejection or infection. The procedure is usually done before discharge from the hospital following transplantation. However, it may also be done during follow-up visits later on.
A CT Scan uses computer-generated X-rays to evaluate whether a kidney is suitable for transplantation by providing detailed information about its shape and size. The procedure does not require anaesthesia or sedation and does not cause discomfort for the patient.
Magnetic Resonance Imaging (MRI) diagnoses kidney transplant complications, including infections, damage to the transplanted organ, or problems with its function.
Magnetic fields and radio waves create a detailed image of the kidneys' position inside the body, allowing doctors to see if there are any problems with the kidneys' function or structure.
Angiography uses contrast dye to confirm the blood flow of the renal artery and ureter. It ensures that the patient's kidneys are functioning correctly after the transplantation.
The contrast dye travels through the body to the kidneys. It shows up on an X-ray as dark areas, allowing doctors to determine if any blockages exist in the kidneys or urinary tract and how well they function post-transplant.
Blood testing is an essential part of any Kidney Transplant Evaluation. The tests determine if the donor and recipient are compatible and can also be used to establish a baseline for future tests. Blood testing also monitors the donor and the recipient during and after the transplant.
Blood testing for kidney transplants involves several different types of tests: ABO Compatibility, Antibody Screen, Crossmatching, Cross-Reactivity Testing, Immunosuppressive Drug Titration, Blood Typing (ABO/Rh), HLA typing (DRB1/DQB1), Serum Creatinine Level (SCr), Urine Protein Level (UP).
Renal Biopsy determines the quality of the kidney transplanted, as transplanting a kidney that is not in good shape can harm the patient.
A renal biopsy takes small tissue samples from different parts of the kidney. The samples go under a microscope for study.
Kidney Transplant Types
Deceased-Donor Kidney Transplant
Deceased-Donor Kidney Transplant enables a kidney transplant from a deceased donor. It treats End-Stage Renal Disease (ESRD) when the patient's kidneys fail to function correctly and needs replacement. The donor's kidney comes from someone who has recently died, or it can come from someone who has been declared brain dead.
Deceased-donor kidney transplantation is considered an option for ESRD patients due to either Diabetes or Glomerulonephritis (Autoimmune Disease). It is also an option for patients with an acute need for Dialysis because they have developed complications requiring immediate treatment.
A Living-Donor Kidney Transplant is a procedure in which a healthy kidney from a living person transplants into a person with kidney failure. A Living Donor Transplant can be done with the donor's permission and without compensation for the donor.
Living-Donor Kidney Transplants help when the recipient has no other options, such as deceased-donor kidneys. The recipient must also be healthy enough to receive a kidney from another person.
The patient must undergo blood tests and an imaging test to ensure that their body will accept the new organ. The patient also may need to take certain medications to prevent rejection of the new organ by their immune system.
A Preemptive Kidney Transplant allows the patient to have their kidney removed and replaced with another. A Preemptive transplant can occur before a patient has developed complete renal failure or while receiving Dialysis.
The procedure involves removing and storing the healthy kidney in cold storage.
The patient's body undergoes a washout of their blood. A healthy kidney transplant happens in the patient's body after washing out. The new kidney will begin producing urine within hours of being transplanted and should be fully functional within two weeks.
Highly Antigenic Kidney Transplant Surgery exchanges a patient's blood with a donor's. This exchange helps to reduce the risk of rejection for patients who have received a kidney transplant. The procedure takes about four hours and involves the removal of about one litre of blood from the patient to replace with approximately 1.5 litres of donor blood.
Highly Antigenic Kidney Transplant Surgery aims to reduce the risk of rejection by exposing the patient's immune system to antigens similar to those found in the donor organ. This exposure helps prevent an immune response against the new organ and allows it to function normally over time.
Re-Transplant and Transplantation in HIV-Positive Patients replace a damaged or failed organ. Re-Transplant is when a previously transplanted organ is removed from the body and transplanted into another person. Transplantation is when an organ not previously transplanted implants into a new recipient's body.
In Re-Transplant, the original donor's body rejects the new organ because it has been out of their body for some time, which causes them to go through a series of treatments to prevent rejection. However, suppose they do not undergo these treatments. In that case, there is a possibility of infection or other complications like Graft Versus Host Disease (GVHD).
An ABO-Incompatible Kidney Transplant enables a patient to receive a kidney from another person with a different blood type when no other option is available.
ABO-incompatible transplantation can treat patients with kidney failure who are not eligible for an ABO-compatible transplant due to other medical conditions or allergies. It can also treat patients on Dialysis for some time who are not yet ready for an ABO-compatible transplant but require a new kidney immediately.
The procedure begins with the surgical removal of the donor's kidney. It ends with the implantation of that organ into the recipient's body. The surgery is performed under general anaesthesia so that both donor and recipient are unconscious during the procedure.
Manipal Hospitals has the best kidney doctors. Our facilities include:
Treatment
Chronic Kidney Disease
Kidney Stones
Polycystic Kidney Disease
Urinary Tract Infections
Kidney Cancer
Auto-Immune Diseases
Dialysis
Haemodialysis
Peritoneal Dialysis
Kidney Transplant
Continuous Renal Replacement Therapy (CRRT)
Lithotripsy (Breaking Kidney Stones)
Ureteral Stenting
Immunosuppressant Medication
Kidney Transplants happen when a patient has severe kidney disease. Doctors will perform a few tests to evaluate the need for a kidney transplant.
A physical test to see how well the kidneys are functioning. If a patient is not able to pass enough urine or if they have high blood pressure, they likely need a transplant.
Doctors also look at blood tests, including Creatinine levels and Blood Urea Nitrogen (BUN) levels, indicating how well your kidneys work.
X-Ray, MRI or CT scans help doctors assess the damage to the kidneys and determine if any scar tissue is present due to previous surgeries. The presence of scar tissue could make it difficult for surgeons to remove the old kidney during surgery and place the new one.
Other tests may be necessary, as well as additional testing with the primary care doctor or a specialist.
Follow the prescriptions given by the doctor.
Follow the diet and exercise guidelines.
Drink plenty of water, eat whole grains, and avoid high-fat foods.
Avoid Smoking and Drinking Alcohol.
The Kidney Transplant is a major surgery and will require time to recover. It takes around two weeks to recover on average. However, it can vary depending on the person.
The patient needs to take medications to prevent rejection and reduce pain during this time. Some side effects may include nausea or headaches.
After recovery, the doctor monitors closely for signs of rejection or infection with regular tests and monitoring.
The first few weeks after a kidney transplant can be difficult because of pain and weakness caused by immunosuppressant medications. To help manage these symptoms, many people choose to have physical therapy before leaving the hospital to get back into their routine as soon as possible after surgery.
There are no long-term exercise restrictions following a kidney transplant. However, as with any major surgery, it is essential to follow the doctor's instructions closely.
The best way to avoid post-transplant complications is by staying in shape before the surgery, as it helps to recover faster and makes it easier to maintain the lifestyle changes required after a transplant.
Kidney transplants offer a number of benefits over dialysis, including:
Improved quality of life
Increased energy levels
Ability to work and travel
Fewer restrictions on diet and fluids
Longer life expectancy
At Manipal Hospital, we have a team of the best nephrologists in Kharadi, Pune, who can answer all your concerns related to the procedure and guide you in your recovery journey.