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The advancement in diagnostic techniques makes it easier to diagnose various diseases promptly, even complex ones. Renal Biopsy is an advanced diagnostic procedure in which a small sample of kidney tissue is obtained for microscopic examination at the lab. Renal Biopsy in Mukundapur is not only done to detect cancer, as usually thought. They are done as they provide crucial information to effectively diagnose and manage various kidney diseases by providing valuable information about their structure, function, and pathology. It is usually done by image-guided minimally invasive methods.
At Manipal Hospitals, Mukundapur, our Nephrology Department has a skilled team of nephrologists trained in performing various diagnostic tests, including Renal Biopsies, using cutting-edge technology to detect diseases and ensure better treatment outcomes. During the procedure, a needle is inserted through the skin and into the kidney to collect a tissue sample, which is then sent to the laboratory for analysis under a microscope by a pathologist. Imaging guidance, such as an Ultrasound or CT scan, is used to ensure accurate needle placement and minimise its related complications. This is an inpatient procedure usually requiring admission for one day for monitoring for complications post-procedure. Renal Biopsy results can provide valuable insights into the underlying cause of kidney disease, guide treatment decisions, and improve patient care.
Certain types of kidney diseases cannot be detected properly through other simple diagnostic tests; thus, a Renal Biopsy is needed. The doctor may suggest a Renal Biopsy for the following conditions:
Abnormal results from a blood test
Transplant kidney evaluation
Haematuria (blood in the urine)
Unexplained kidney dysfunction
Glomerular disease and nephrotic syndrome
Acute or chronic kidney disease
Evaluate medication side effects on kidneys
Checking kidney damage
Assessing kidney tumours
Proteinuria (protein in urine)
Monitoring kidney treatment responses
Kidney disease with an unknown case
In Renal Biopsy, the sample can be collected in two ways:
Percutaneous Biopsy: This is the most common type of Renal Biopsy, in which the sample is taken by inserting the needle into the outer layer of the kidney and directed to the right location in the kidney with the help of ultrasound imaging.
Open Biopsy: It is a surgical method to obtain a sample directly from the kidney by making a small incision under the effect of anaesthesia. It is used in rare cases, especially at the time of a Kidney Transplant.
The healthcare provider will explain the Renal Biopsy procedure to you and address any questions or concerns that you may have.
The provider may conduct a physical examination to ensure your health. Additionally, blood tests, urine tests, or other diagnostic tests may be performed.
If you have any allergies or sensitivity to any medications, anaesthesia, latex, or tape, inform the provider beforehand.
Disclose all medications, including prescription, over-the-counter, vitamins, and herbal supplements, to your healthcare provider.
Inform your healthcare provider if you have a history of bleeding disorders or if you are taking any blood-thinning medications, aspirin, or other drugs that affect blood clotting. You may need to discontinue these medications before the biopsy.
If you are pregnant or suspect you might be pregnant, inform your healthcare provider beforehand.
Adhere to any instructions provided by the healthcare team regarding fasting or abstaining from drinking before the biopsy.
Before the procedure, you may be administered a sedative to help you relax. Arrange for someone to drive you home, as the sedative may cause drowsiness.
Depending on your health condition, your healthcare team may request additional, specific preparations.
You will have to change into a hospital gown.
An intravenous (IV) line will be attached to your arm or hand.
You will be asked to lie on your stomach for easy access to the kidney; a pillow may be used for support. If you have a transplanted kidney, lie on your back.
Before starting the procedure, the biopsy site will be disinfected with an antiseptic solution.
The method of needle insertion may differ depending on the type of biopsy being done.
You will feel a needle stick when the local anaesthetic is injected, causing a brief stinging sensation.
You have to remain still throughout the procedure.
The provider will use ultrasounds or CT to guide the needle into the kidney.
Inhale and hold your breath while the healthcare provider inserts the biopsy needle to prevent diaphragm movement.
You will experience mild pain or pressure during sample collection.
You will have to undergo multiple punctures if additional tissue samples are required, repeating the same process.
The provider will apply firm pressure to the biopsy site after needle removal to stop bleeding.
Afterwards, a sterile bandage or dressing will be applied, and the sample of kidney tissue will be sent to the diagnostic lab for testing.
The recovery process depends on the type of procedure and the healthcare provider's protocols.
You will be transferred to a recovery room for close monitoring until the effects of the anaesthesia wear off.
Once your vital signs stabilise and you are fully alert, you may be moved to a hospital room or discharged to go home.
You will likely need to lie on your back for several hours post-procedure.
A nurse will monitor your urine for signs of bleeding, and blood tests may be conducted to check for internal bleeding.
Depending on your condition, you may be discharged the same day or the following day– an overnight stay is usually advised to monitor for complications.
If you have received sedation or anaesthesia, arrange for someone to drive you home.
The biopsy site may feel tender or sore for several days afterwards.
Take pain medication as prescribed by our healthcare provider, and avoid aspirin or other medications that may increase bleeding risk.
Follow our healthcare team's instructions regarding medication usage.
Just like other procedures, the risks with Renal Biopsy are less but can occur, including:
Fever
Excessive bleeding
A hole in nearby organs or structures
Dizziness
Urine infection
Inability to urinate
Bruising or pain at the biopsy site
Infection near the biopsy site
Arteriovenous fistula
It involves the insertion of a small needle and is usually done under local anaesthesia, so you would not feel any pain or discomfort. However, some patients may experience pain or discomfort at the biopsy site afterwards.
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