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At Manipal Hospitals, Mukundapur, we specialise in diagnosing, treating, and managing a wide range of kidney and urinary tract disorders in children. Our expertise covers conditions such as kidney failure, high blood pressure, inherited kidney diseases, kidney stones, urinary tract infections, and urine abnormalities like the presence of blood or protein. Certain factors increase a child’s risk for acute kidney diseases, including blood loss, shock, urinary tract blockages, medications that affect kidney function, cardiac arrest, glomerulonephritis, and haemolytic uremic syndrome. Ensuring your child is in the hands of skilled paediatric nephrologists can significantly impact their recovery and long-term health.
Our team at the Department of Paediatric Nephrology, Manipal Hospitals, is exceptionally trained in paediatric nephrology and is renowned for managing even the most complex kidney conditions. Whether your child requires Renal Replacement Therapy for acute kidney injury, Dialysis, or a Kidney Transplant due to end-stage kidney disease, our specialists are proficient in performing these interventions with a high success rate.
Kidney disease, also known as renal failure, involves either short-term or permanent damage to the kidneys, leading to a loss of normal kidney function. There are two different types:
Acute kidney disease: This type occurs suddenly and, in some cases, can be reversed, allowing the kidneys to return to normal function.
Chronic kidney disease: This type progresses gradually over at least three months and can lead to permanent kidney failure.
Acute kidney disease in children can be caused by:
Reduced blood flow to the kidneys due to factors like blood loss, surgery, or shock
A blockage in the urinary tract
Medicines that may harm the kidneys
Conditions that reduce or block oxygen and blood supply to the kidneys, such as cardiac arrest
Haemolytic uremic syndrome, which is often caused by an E. coli infection, causes kidney failure by blocking the small structures and vessels in the kidney.
Glomerulonephritis: It occurs in parts of the kidneys called glomeruli, which become inflamed, impairing the kidney’s function to filter urine
Chronic kidney disease in children is caused by:
A long-term blockage in the urinary tract
Alport syndrome is an inherited disorder that leads to hearing loss, progressive kidney damage, and eye defects.
Nephrotic syndrome causes protein in the urine, low protein levels in the blood, high cholesterol levels, and tissue swelling.
Polycystic kidney disease is a genetic disorder that causes multiple fluid-filled cysts in the kidneys.
Cystinosis is an inherited disorder where the amino acid cysteine collects in the kidney cell’s lysosomes.
Other chronic conditions, such as untreated diabetes or high blood pressure, can lead to kidney problems, which can reduce oxygen and blood flow to the kidneys.
Your child is at higher risk for acute kidney disease if they have:
Urinary tract blockage
Blood loss, surgery, or shock
Taken medicines that can cause kidney problems
A condition that reduces or blocks oxygen and blood supply to the kidneys, such as cardiac arrest
Haemolytic uremic syndrome
Glomerulonephritis
Polycystic kidney disease
Cystinosis
Untreated diabetes
Untreated high blood pressure
Untreated acute kidney disease
Children experience various symptoms of acute and chronic kidney disease that may resemble other health conditions. Make sure to consult a healthcare provider for an accurate and timely diagnosis.
Common symptoms of acute kidney disease include:
Fever
Rash
Bloody diarrhoea
Severe vomiting
Stomach pain
Either no urine or lots of urine
Pale skin
Tissue swelling
Eye inflammation
The symptoms of chronic kidney disease include:
Poor appetite
Vomiting
Bone pain
Headache
Stunted growth
Malaise
Excess urine or no urine
Recurrent urinary tract infections
Urinary incontinence
Pale skin
Bad breath
Hearing problems
Stomach mass
Tissue swelling
Irritability
Poor muscle tone
Change in mental alertness
Your child's healthcare provider can ask about your child’s symptoms and health history and conduct a physical exam. Your child may also have to undergo certain tests, such as:
Blood tests that include blood cell counts, electrolyte levels, and kidney function.
Urine test
Renal ultrasound (sonography) is a painless procedure that uses sound waves to create images of body tissues, allowing your healthcare provider to see the size, shape, and presence of growth, kidney stones, cysts, or other problems.
Renal Biopsy: A small sample of kidney tissue is taken either through a needle or during surgery and seen under a microscope.
Since the kidneys have many functions, kidney failure can lead to various complications, including:
Low red blood cell count
Problems in the heart and blood vessels
Bone disease
Pain in the bones, joints, and muscles
Decreased mental function, including confusion and dementia
Nerve damage in the arms and legs
A greater risk of getting infections
Poor nutrition
Skin changes, including dryness and itching
You should consult a paediatric nephrologist if your child has symptoms of kidney problems, has been diagnosed with kidney disease, or if a primary care physician recommends a specialised evaluation.
With proper treatment, many children with chronic kidney disease (CKD) can lead relatively normal lives. However, they will need ongoing medical care, lifestyle adjustments, and possibly long-term treatments like Dialysis or a Kidney Transplant.
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